Additional craniofacial findings include widely spaced eyes (hypertelorism), incomplete closure of the roof of the mouth (cleft palate), an abnormal groove in the upper lip (cleft lip), and/or underdevelopment of the middle area of the face (midface hypoplasia). Abnormalities of the middle and inner ears may also be present including hearing loss. Some affected infants may display small, low-set ears (microtia) with narrowing (stenosis) of the ear canals or are born missing ears. Affected infants may not have all of the symptoms listed below. The specific symptoms and physical findings can vary from one infant to another. Additional anomalies may include renal, thymus gland abnormality and parathyroid gland abnormalities.Ĭharacteristic features of infants with fetal retinoid syndrome include abnormalities of the craniofacial region, CNS, and cardiovascular system. However, characteristic features may include growth delay before and after birth (intrauterine growth restriction and postnatal growth retardation) malformations of the skull and facial (craniofacial) region central nervous system (CNS) abnormalities heart abnormalities and/or additional physical findings. The range and severity of associated abnormalities are variable. Isotretinoin and its commercially available brands, although effective in the treatment of acne, can cause developmental abnormalities in the fetus (teratogenic effects) and therefore should not be used during pregnancy due to the risk of birth defects. The most well-known retinoid is isotretinoin (commonly referred to by one of its former brand names, Accutane or Roaccutane, a drug used to treat severe cystic acne.
Not good timing synonym skin#
Retinoids are the synthetic (man-made) forms of vitamin A used to treat various skin (dermatological) conditions. Overall malformation rates in live-born infants from prospectively reported pregnancies range from 5% to 20%. The absolute risk of congenital malformations following oral isotretinoin therapy is currently unclear.
Information on Clinical Trials and Research Studies.Personally, I'd use your final suggestion. Let me know: what is / when is a good time for you to do a remote support session?īut I bet none of them shrinks from using 'Let me know what's happening'. Let me know what's / when's a good time for you to do a remote support session.Īre both commonly used grammatical traditionalists might argue for Let me know when a good time for you to do a remote support session would be. It may sometimes sound informal, but is colloquial, and may sometimes even disambiguate: Tactile and multi-sensory objects for you to investigate in the Roman We can let you know what is a good time, and arrange to have some Space, please let us know what is a good time for you to get If you can give of your time helping to maintain this wonderful What is a good time for you to meet at B & N on Thursday You don't ' need' 'when' ''what' is commonly used with expressions of time: Every method I can think of just doesn't sound right to me and the last thing I want is for my question to be confusing to the people I'm trying to help.
Not good timing synonym how to#
What is the best time to schedule a remote support session with you?įrankly, I'm at a loss as to how to word this question. Here's one attempt at asking my question based around what that user said: That user claims that "what" is much more specific and may be the word I should use.
I also found a discussion on where one of the users describes the difference between using the word "when" as opposed to the word "what". Please tell me a date and time that you can be available to demonstrate the problem you encountered. I'd like to schedule a remote support session with you. To accomplish this, do I have to expand on my question and break it down into sections? When is a good time for you to do a remote support session?īut I don't think it emphasizes that I need a specific time returned to me rather than a generic "I'm usually available around lunch time" response. I found this similar question that makes me think I could probably just say this: Let me know when a good time for you to do a remote support session is. I'm looking for the grammatically correct way of asking this question:
As an IT person, I quite frequently have to schedule availability based support calls with remote users.
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